Assay Detail
Functional
CHEMBL756822
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Inhibitory activity against IgE antibody production in PBMC
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel naphthalene derivatives as inhibitors of human immunoglobulin E antibody production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.82 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL336392 | — | — | 1 | 5.92 |
| CHEMBL337497 | — | — | 1 | 5.80 |
| CHEMBL133470 | — | — | 1 | 5.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL336392 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL337497 | — | IC50 | = | 1570.0 | nM | 5.80 |
| CHEMBL133470 | — | IC50 | = | 1880.0 | nM | 5.73 |