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Assay Detail

CHEMBL756983

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested for toxicity in peripheral blood mononuclear cells.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Activity of acyclic 6-(phenylselenenyl)pyrimidine nucleosides against human immunodeficiency viruses in primary lymphocytes.
Goudgaon NM, Schinazi RF.
J Med Chem (1991) 34 : 3305 -3309
PubMed 1720175 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.09 4.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273401 1 4.17
CHEMBL278418 1 4.00
CHEMBL320766 1 -
CHEMBL31871 HEPT 1 -
CHEMBL11762 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273401 IC50 = 67000.0 nM 4.17
CHEMBL278418 IC50 = 100000.0 nM 4.00
CHEMBL320766 IC50 > 100000.0 nM -
CHEMBL31871 HEPT IC50 > 100000.0 nM -
CHEMBL11762 IC50 > 100000.0 nM -