Assay Detail
Binding
CHEMBL757345
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.21 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL438925 | — | — | 1 | 7.89 |
| CHEMBL412459 | — | — | 1 | 6.57 |
| CHEMBL262404 | — | — | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL438925 | — | Ki | = | 12.88 | nM | 7.89 |
| CHEMBL412459 | — | Ki | = | 269.15 | nM | 6.57 |
| CHEMBL262404 | — | Ki | = | 66069.34 | nM | 4.18 |