Compound Detail
CHEMBL262404
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O
Basic Information
| ChEMBL ID | CHEMBL262404 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | NCXUXUKCCASIQQ-SZLTWBEZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1585.8
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Orexin/Hypocretin receptor type 1 CHEMBL5113 | Ki | 4.18 | 4.18 | 66069.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Orexin/Hypocretin receptor type 1 | Ki | = | 66069.34 | nM | 4.18 | Binding affinity to Orexin receptor type 1 was determined using laser scanning c... | 11266181 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11266181 | 10.1016/s0960-894x(01)00043-9 | CHO | 1 |
| 11266181 | 10.1016/s0960-894x(01)00043-9 | Orexin/Hypocretin receptor type 1 | 1 |
Data from ChEMBL 36 via Core Engine