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Assay Detail

CHEMBL757424

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Functional
Compound was tested for inhibition of HIV isolate BCF01 in peripheral blood mononuclear cells (PBMC)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. III: synthesis, antiviral and pharmacokinetic profiles of symmetrical heteroaryl carboxamides.
McCombie SW, Tagat JR, Vice SF, Lin SI, Steensma R, Palani A, Neustadt BR, Baroudy BM, Strizki JM, Endres M, Cox K, Dan N, Chou CC.
Bioorg Med Chem Lett (2003) 13 : 567 -571
PubMed 12565973 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL311795 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL311795 IC50 = 200.0 nM 6.70