Assay Detail
Binding
CHEMBL757700
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The binding affinity was measured using [3H]- DAGO against Opioid receptor mu 1 of rat brain
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformationally constrained deltorphin analogs with 2-aminotetralin-2-carboxylic acid in position 3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.73 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433978 | — | — | 1 | 6.18 |
| CHEMBL369499 | — | — | 1 | 6.14 |
| CHEMBL426776 | — | — | 1 | 5.75 |
| CHEMBL433720 | — | — | 1 | 5.50 |
| CHEMBL175116 | — | — | 1 | 5.49 |
| CHEMBL177647 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433978 | — | Ki | = | 660.0 | nM | 6.18 |
| CHEMBL369499 | — | Ki | = | 731.0 | nM | 6.14 |
| CHEMBL426776 | — | Ki | = | 1799.0 | nM | 5.75 |
| CHEMBL433720 | — | Ki | = | 3188.0 | nM | 5.50 |
| CHEMBL175116 | — | Ki | = | 3224.0 | nM | 5.49 |
| CHEMBL177647 | — | Ki | = | 4526.0 | nM | 5.34 |