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Assay Detail

CHEMBL757714

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for its ability to inhibit the replication of the HIV-1 strain HTLV111B in human peripheral blood mononuclear cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a major determinant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase.
Venkatachalam TK, Sudbeck EA, Mao C, Uckun FM.
Bioorg Med Chem Lett (2000) 10 : 2071 -2074
PubMed 10999473 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL294743 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL294743 IC50 = 1.0 nM 9.00