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Assay Detail

CHEMBL757799

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity in PBM cells expressed as IC50
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PBM
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Synthesis and antiviral evaluation of 4-hydroxymethyl-2, 3-dideoxy-3-thianucleosides and their cyclic monophosphates
Chao Q, Nair V
Bioorg Med Chem Lett (1997) 7 : 1199 -1202
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.69 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL141 LAMIVUDINE 4.0 2 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL141 LAMIVUDINE IC50 = 2.0 nM 8.70
CHEMBL141 LAMIVUDINE IC50 = 210.0 nM 6.68