Assay Detail
Functional
CHEMBL757801
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit 50% of human peripheral blood mononuclear cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anti-human immunodeficiency and anti-hepatitis B virus activities of -l-2,3-dideoxy purine nucleosides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.23 | 4.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290427 | — | — | 1 | 4.23 |
| CHEMBL45254 | — | — | 1 | 4.22 |
| CHEMBL78101 | — | — | 1 | - |
| CHEMBL45071 | — | — | 1 | - |
| CHEMBL23094 | — | — | 1 | - |
| CHEMBL1460 | DIDANOSINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290427 | — | IC50 | = | 59000.0 | nM | 4.23 |
| CHEMBL45254 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL78101 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL45071 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL23094 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1460 | DIDANOSINE | IC50 | > | 100000.0 | nM | - |