Assay Detail
Binding
CHEMBL757986
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Compound was evaluated for binding affinity towards Opioid receptor mu 1 by displacement of [3H]-DAMGO radioligand
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
4-[(8-Alkyl-8-azabicyclo[3.2.1]octyl-3-yl)-3-arylanilino]-N,N-diethylbenzamides: high affinity, selective ligands for the delta opioid receptor illustrate factors important to antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.82 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085002 | — | — | 1 | 6.16 |
| CHEMBL3085003 | — | — | 1 | 5.96 |
| CHEMBL13470 | SNC-80 | — | 1 | 5.79 |
| CHEMBL3085004 | — | — | 1 | 5.59 |
| CHEMBL22650 | — | — | 1 | 5.58 |
| CHEMBL280698 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085002 | — | Ki | = | 686.0 | nM | 6.16 |
| CHEMBL3085003 | — | Ki | = | 1105.0 | nM | 5.96 |
| CHEMBL13470 | SNC-80 | Ki | = | 1614.0 | nM | 5.79 |
| CHEMBL3085004 | — | Ki | = | 2547.0 | nM | 5.59 |
| CHEMBL22650 | — | Ki | = | 2623.0 | nM | 5.58 |
| CHEMBL280698 | — | Ki | > | 3400.0 | nM | - |