Assay Detail
Binding
CHEMBL757987
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Compound was evaluated for its ability to displace [3H]DAMGO in C6 glioma cells expressing the cloned Opioid receptor mu 1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | C6 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.89 | 8.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | — | 1 | 8.43 |
| CHEMBL80116 | — | — | 1 | 8.14 |
| CHEMBL79443 | — | — | 1 | 5.72 |
| CHEMBL81355 | — | — | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL80116 | — | Ki | = | 7.3 | nM | 8.14 |
| CHEMBL79443 | — | Ki | = | 1925.0 | nM | 5.72 |
| CHEMBL81355 | — | Ki | = | 5330.0 | nM | 5.27 |