Assay Detail
Binding
CHEMBL758269
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Inhibitory activity towards Opioid receptor mu 1 using guinea pig ileum (GPI) assay was determined for the compound
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Structure-activity relationships of cyclic opioid peptide analogues containing a phenylalanine residue in the 3-position.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.90 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL302408 | — | — | 1 | 7.19 |
| CHEMBL15595 | — | — | 1 | 6.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL302408 | — | IC50 | = | 64.7 | nM | 7.19 |
| CHEMBL15595 | — | IC50 | = | 246.0 | nM | 6.61 |