Assay Detail
Binding
CHEMBL758670
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Tested for Oxidosqualene-lanosterol cyclase inhibition in Pneumocystis carinii
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pneumocystis carinii |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Oxidosqualene cyclase inhibitors as antimicrobial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.73 | 8.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL135109 | — | — | 1 | 8.34 |
| CHEMBL25405 | — | — | 1 | 7.04 |
| CHEMBL132091 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL135109 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL25405 | — | IC50 | = | 92.0 | nM | 7.04 |
| CHEMBL132091 | — | IC50 | = | 16000.0 | nM | 4.80 |