Assay Detail
Functional
CHEMBL758935
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Antiviral activity against HIV in human peripheral blood mononuclear cells (PBMC)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anti-human immunodeficiency and anti-hepatitis B virus activities of -l-2,3-dideoxy purine nucleosides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.41 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290427 | — | — | 1 | 6.42 |
| CHEMBL45254 | — | — | 1 | 5.26 |
| CHEMBL23094 | — | — | 1 | 5.09 |
| CHEMBL45071 | — | — | 1 | 4.85 |
| CHEMBL78101 | — | — | 1 | - |
| CHEMBL1460 | DIDANOSINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290427 | — | EC50 | = | 380.0 | nM | 6.42 |
| CHEMBL45254 | — | EC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL23094 | — | EC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL45071 | — | EC50 | = | 14100.0 | nM | 4.85 |
| CHEMBL78101 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL1460 | DIDANOSINE | EC50 | > | 100000.0 | nM | - |