Assay Detail
Functional
CHEMBL759522
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The compound was evaluated for antagonist activity against recombinant human receptor P2X purinoceptor 2 (P2X2 )
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Purine and pyrimidine (P2) receptors as drug targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.04 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339386 | — | — | 1 | 5.26 |
| CHEMBL339385 | DIADENOSINE TETRAPHOSPHATE | — | 1 | 4.82 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | 0.5 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339386 | — | EC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL339385 | DIADENOSINE TETRAPHOSPHATE | EC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | EC50 | > | 100000.0 | nM | - |