Assay Detail
Binding
CHEMBL759831
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Compound was tested for it''s ability to inhibit [3H]C18-PAF binding to PMN membrane receptors
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of MK 287 (L-680,573): a potent, specific and orally active paf receptor antagonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.86 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL299944 | — | — | 1 | 8.49 |
| CHEMBL109738 | — | — | 1 | 7.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL299944 | — | Ki | = | 3.2 | nM | 8.49 |
| CHEMBL109738 | — | Ki | = | 59.0 | nM | 7.23 |