Compound Detail
CHEMBL109738
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Basic Information
| ChEMBL ID | CHEMBL109738 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WXIDMVGKJBAEFP-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
510.6
MW (Da)
3.87
ALogP
9
HBA
1
HBD
109.8
PSA (Ų)
0.45
QED
1
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.23
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL250 | Ki | 7.23 | 7.085 | 59.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | Ki | = | 59.0 | nM | 7.23 | Compound was tested for it''s ability to inhibit [3H]C18-PAF binding to PMN memb... | - |
| Platelet-activating factor receptor | Ki | = | 116.0 | nM | 6.94 | Compound was tested for it''s ability to inhibit [3H]C18-PAF binding to human pl... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80818-0 | Platelet-activating factor receptor | 2 |
Data from ChEMBL 36 via Core Engine