Assay Detail
Functional
CHEMBL759882
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Inhibitory activity against platelet aggregation, induced by U-46619 in human platelet rich plasma
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.87 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418585 | — | — | 1 | 8.22 |
| CHEMBL30743 | — | — | 1 | 7.89 |
| CHEMBL416943 | — | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418585 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL30743 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL416943 | — | IC50 | = | 31.0 | nM | 7.51 |