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Assay Detail

CHEMBL760308

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Relaxant effect on PGF2-alpha precontracted pig coronary arteries
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Sus scrofa
Confidence 1 — Organism
Curated By Expert

Target

Sus scrofa (CHEMBL613488)
Type ORGANISM
Organism Sus scrofa

Publication

Cyclic GMP phosphodiesterase inhibitors. 1. The discovery of a novel potent inhibitor, 4-((3,4-(methylenedioxy)benzyl)amino)-6,7,8-trimethoxyquinazoline.
Takase Y, Saeki T, Fujimoto M, Saito I.
J Med Chem (1993) 36 : 3765 -3770
PubMed 8254606 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.71 5.71

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL302299 1 5.71

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL302299 EC50 = 1960.0 nM 5.71