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Target Snapshot

CHEMBL613488 Target Snapshot

Sus scrofa · ORGANISM · Sus scrofa

472Compounds
343Assays
7Approved Drugs
182.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Sus scrofa as ChEMBL target CHEMBL613488. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Sus scrofa
ORGANISM · Sus scrofa
As of 2026-09-14
ChEMBL target ID
CHEMBL613488
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Sus scrofa still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSus scrofa
UniProt AccessionN/A

Sus scrofa

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Sus scrofa.

Review nameSus scrofa
OrganismSus scrofa
Clinical Profile

Clinical Phase Distribution

7
Approved
2
Phase III
8
Phase II
Assay Mix

Activity Type Distribution

IC50113.0
EC5064.0
KD5.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1484 9.52 IC50 0.3 Approved
CHEMBL3350238 8.82 IC50 1.5 Preclinical
CHEMBL2093965 8.6 IC50 2.5 Preclinical
CHEMBL72 8.49 IC50 3.2 Approved
CHEMBL193 8.44 IC50 3.6 Approved
CHEMBL553942 8.42 IC50 3.8 Preclinical
CHEMBL106121 8.4 IC50 4.0 Preclinical
CHEMBL30911 8.4 IC50 4.0 Preclinical
CHEMBL540511 8.4 IC50 4.0 Preclinical
CHEMBL554455 8.35 IC50 4.5 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
14
5.5
20
6.0
22
6.5
14
7.0
15
7.5
11
8.0
2
8.5
0
9.0
1
9.5
pChEMBL
Approved Drugs

Approved Drugs

VILOXAZINE
CHEMBL306700
Approved 2021
SILDENAFIL CITRATE
CHEMBL1737
Approved 1998
NICARDIPINE
CHEMBL1484
Approved 1988
NIFEDIPINE
CHEMBL193
Approved 1981
PROBUCOL
CHEMBL608
Approved 1977
DESIPRAMINE
CHEMBL72
Approved 1964
Assay Landscape

Assay Landscape

349
Total Assays
107
Tested Compounds
3
Assay Types
ADME — 176 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 176 0
Functional — 163 assays, 107 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 163 107 6.5
Toxicity — 10 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 10 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine