Assay Detail
Binding
CHEMBL760425
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Compound was tested for displacement of 3[H] oxytocin from rat OT receptor (in vitro)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.83 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL284442 | — | — | 1 | 6.13 |
| CHEMBL31065 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL284442 | — | IC50 | = | 744.0 | nM | 6.13 |
| CHEMBL31065 | — | IC50 | = | 3040.0 | nM | 5.52 |