Assay Detail
Binding
CHEMBL760426
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Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissue
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent, non-peptidic oxytocin receptor antagonists from a natural source
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.81 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL115277 | — | — | 1 | 5.30 |
| CHEMBL116226 | — | — | 1 | 5.08 |
| CHEMBL326085 | — | — | 1 | 4.68 |
| CHEMBL325752 | PENICILLIDE | — | 1 | 4.17 |
| CHEMBL331591 | — | — | 1 | - |
| CHEMBL326142 | — | — | 1 | - |
| CHEMBL117045 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL115277 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL116226 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL326085 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL325752 | PENICILLIDE | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL331591 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL326142 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL117045 | — | IC50 | > | 100000.0 | nM | - |