Assay Detail
Binding
CHEMBL760454
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitor concentration required to block 50% of the specific [3H]PAF binding to rabbit platelet membranes.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Platelet-activating factor receptor (CHEMBL5136) ↗| Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
Publication
Structure-activity relationships of kadsurenone analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.92 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296958 | KADSURENONE | — | 1 | 6.92 |
| CHEMBL287709 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296958 | KADSURENONE | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL287709 | — | IC50 | = | 7e-05 | nM | - |