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Assay Detail

CHEMBL760455

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitor concentration required to block 50% of the specific [3H]PAF binding, obtained as natural product.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Platelet-activating factor receptor (CHEMBL5136)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Structure-activity relationships of kadsurenone analogues.
Ponpipom MM, Bugianesi RL, Brooker DR, Yue BZ, Hwang SB, Shen TY.
J Med Chem (1987) 30 : 136 -142
PubMed 3027330 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296958 KADSURENONE 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296958 KADSURENONE IC50 = 100.0 nM 7.00