Assay Detail
Binding
CHEMBL760614
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305881 | — | — | 1 | 4.00 |
| CHEMBL7393 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305881 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL7393 | — | IC50 | = | 100000.0 | nM | 4.00 |