Lysosomal Pro-X carboxypeptidase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P42785. Use UniProt P42785 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P42785 as the stable identity anchor, then attach disease evidence before program review.
Lysosomal Pro-X carboxypeptidase
Review this target as Lysosomal Pro-X carboxypeptidase, mapped to UniProt P42785. Sequence length is 496 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysosomal Pro-X carboxypeptidase as ChEMBL target CHEMBL2335, mapped to UniProt P42785. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Lysosomal Pro-X carboxypeptidase is the right protein anchor across sources, using UniProt P42785 as the stable mapping.
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| Preferred Name | Lysosomal Pro-X carboxypeptidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P42785 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysosomal Pro-X carboxypeptidase |
| UniProt Accession | P42785 |
| Component Type | Protein |
| Sequence Length | 496 aa |
Lysosomal Pro-X carboxypeptidase
Review this target as Lysosomal Pro-X carboxypeptidase, mapped to UniProt P42785. Sequence length is 496 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3910523 | 10.46 | IC50 | 0.035 | Preclinical |
| CHEMBL3919329 | 10.29 | IC50 | 0.051 | Preclinical |
| CHEMBL3086040 | 10.1 | IC50 | 0.079 | Preclinical |
| CHEMBL1950440 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL3086037 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL3652599 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL2022787 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL2022793 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL2023210 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL1938522 | 9.52 | IC50 | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 37 | 399 | 7.4 |
| tissue-based format | 4 | 9 | 6.2 |
| assay format | 3 | 24 | 8.5 |
| cell-based format | 2 | 27 | 4.5 |