Assay Detail
Binding
CHEMBL760764
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of rat polymorphonuclear leukocyte (PMN) Prostaglandin G/H synthase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.91 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL284706 | — | — | 1 | 5.21 |
| CHEMBL33734 | — | — | 1 | 5.13 |
| CHEMBL287012 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL284706 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL33734 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL287012 | — | IC50 | = | 40000.0 | nM | 4.40 |