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Assay Detail

CHEMBL760809

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonistic activity against human progesterone receptor expressed in CV-1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CV-1
Confidence 9 — Direct single protein target
Curated By Expert

Target

Progesterone receptor (CHEMBL208)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.
Zhi L, Tegley CM, Pio B, Edwards JP, Motamedi M, Jones TK, Marschke KB, Mais DE, Risek B, Schrader WT.
J Med Chem (2003) 46 : 4104 -4112
PubMed 12954062 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.82 9.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL717 MEDROXYPROGESTERONE ACETATE 4.0 1 9.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL717 MEDROXYPROGESTERONE ACETATE EC50 = 0.15 nM 9.82