Assay Detail
Binding
CHEMBL760925
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Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human brain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.07 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150093 | — | — | 1 | 5.40 |
| CHEMBL332898 | — | — | 1 | 5.02 |
| CHEMBL151056 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150093 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL332898 | — | Ki | = | 9500.0 | nM | 5.02 |
| CHEMBL151056 | — | Ki | = | 16000.0 | nM | 4.80 |