Assay Detail
Functional
CHEMBL760968
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against HIV-1 replication in phytohemagglutininin-activated peripheral blood mononuclear (PHA-PBM) cells
3
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis, absolute configuration, and enantioselectivity of antiretroviral effect of (R)-(-)- and (S)-(+)-cytallene. Lipase-catalyzed enantioselective acylations of (+/-)-N4-acylcytallenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.25 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29288 | — | — | 3 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29288 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL29288 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL29288 | — | IC50 | > | 10000.0 | nM | - |