Assay Detail
Functional
CHEMBL761200
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Tested in vitro against PC-9 human lung adenocarcinoma
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.00 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 5.18 |
| CHEMBL1204346 | — | — | 1 | 4.82 |
| CHEMBL337389 | — | — | 1 | - |
| CHEMBL1790974 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL1204346 | — | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL337389 | — | IC50 | > | 360000.0 | nM | - |
| CHEMBL1790974 | — | IC50 | > | 430000.0 | nM | - |