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Assay Detail

CHEMBL762230

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxic concentration in vitro in well-oxygenated mammalian cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Relationships between structure and kinetics of cyclization of 2-aminoaryl amides: potential prodrugs of cyclization-activated aromatic mustards.
Atwell GJ, Sykes BM, O'Connor CJ, Denny WA.
J Med Chem (1994) 37 : 371 -380
PubMed 8308863 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.08 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL275497 1 7.16
CHEMBL21048 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL275497 IC50 = 70.0 nM 7.16
CHEMBL21048 IC50 = 10000.0 nM 5.00