Assay Detail
Binding
CHEMBL762330
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Compound was measured for the inhibition of pepsin hydrolysis of hemoglobin.
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New pepstatin analogues: synthesis and pepsin inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.40 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296588 | PEPSTATIN | 2.0 | 1 | 8.15 |
| CHEMBL72555 | — | — | 1 | 8.00 |
| CHEMBL74075 | — | — | 1 | 6.70 |
| CHEMBL72563 | — | — | 1 | 6.38 |
| CHEMBL74043 | — | — | 1 | 4.75 |
| CHEMBL73985 | — | — | 1 | 4.41 |
| CHEMBL75248 | — | — | 1 | - |
| CHEMBL306067 | — | — | 1 | - |
| CHEMBL74149 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296588 | PEPSTATIN | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL72555 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL74075 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL72563 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL74043 | — | IC50 | = | 17700.0 | nM | 4.75 |
| CHEMBL73985 | — | IC50 | = | 39400.0 | nM | 4.41 |
| CHEMBL75248 | — | IC50 | = | 346000.0 | nM | - |
| CHEMBL306067 | — | IC50 | = | 1130000.0 | nM | - |
| CHEMBL74149 | — | IC50 | = | 1540000.0 | nM | - |