Assay Detail
Binding
CHEMBL762416
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibitory activity against Prostaglandin G/H synthase in human polymorphonuclear leukocytes[PMNS]
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.07 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314337 | — | — | 1 | 8.70 |
| CHEMBL274642 | BW-755C | — | 1 | 4.92 |
| CHEMBL313245 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314337 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL274642 | BW-755C | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL313245 | — | IC50 | = | 25000.0 | nM | 4.60 |