Assay Detail
Functional
CHEMBL762454
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory activity against rat polymorphonuclear leukocyte Prostaglandin G/H synthase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.32 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL55133 | — | — | 1 | 4.52 |
| CHEMBL293296 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL55133 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL293296 | — | IC50 | = | 75000.0 | nM | 4.12 |