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Assay Detail

CHEMBL762797

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration required to inhibit HDJ2 farnesylation in PSN-1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PSN-1
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Protein farnesyltransferase (CHEMBL2094108)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?
Bell IM.
J Med Chem (2004) 47 : 1869 -1878
PubMed 15055985 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.74 9.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL442552 1 9.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL442552 EC50 = 0.18 nM 9.74