Assay Detail
Binding
CHEMBL763067
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Inhibition of Prostaglandin G/H synthase activity in sheep seminal vesicle was determined 100 uM
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Ovis aries |
| Tissue | Seminal vesicle |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.24 | 4.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339587 | — | — | 1 | 4.36 |
| CHEMBL130640 | — | — | 1 | 4.20 |
| CHEMBL128012 | — | — | 1 | 4.15 |
| CHEMBL128000 | BUTEIN | — | 1 | - |
| CHEMBL129795 | ISOLIQUIRITIGENIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339587 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL130640 | — | IC50 | = | 63000.0 | nM | 4.20 |
| CHEMBL128012 | — | IC50 | = | 71000.0 | nM | 4.15 |
| CHEMBL128000 | BUTEIN | IC50 | = | 120000.0 | nM | - |
| CHEMBL129795 | ISOLIQUIRITIGENIN | IC50 | = | 130000.0 | nM | - |