Assay Detail
Functional
CHEMBL763187
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity at Prostanoid EP2 receptor in human was determined
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Prostaglandin E2 receptor EP2 subtype (CHEMBL1881) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-activity relationship on the human EP3 prostanoid receptor by use of solid-support chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.89 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL350832 | — | — | 1 | 5.39 |
| CHEMBL423815 | — | — | 1 | 4.92 |
| CHEMBL166351 | — | — | 1 | 4.89 |
| CHEMBL165010 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL350832 | — | Ki | = | 4100.0 | nM | 5.39 |
| CHEMBL423815 | — | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL166351 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL165010 | — | Ki | = | 43000.0 | nM | 4.37 |