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Assay Detail

CHEMBL763286

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of ADP-induced human platelet rich plasma aggregation in presence of 100 uM ODQ
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Plasma
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin.
Cena C, Lolli ML, Lazzarato L, Guaita E, Morini G, Coruzzi G, McElroy SP, Megson IL, Fruttero R, Gasco A.
J Med Chem (2003) 46 : 747 -754
PubMed 12593655 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 10.86 10.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL351742 1 10.86
CHEMBL165969 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL351742 IC50 = 0.0138 nM 10.86
CHEMBL165969 IC50 = 0.004266 nM -