Assay Detail
Binding
CHEMBL764185
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Inhibition of [3H]R5020 binding to rabbit uterine progesterone receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and evaluation of potential radioligands for the progesterone receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.92 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45777 | — | — | 1 | 8.74 |
| CHEMBL295827 | — | — | 1 | 8.37 |
| CHEMBL103 | PROGESTERONE | 4.0 | 1 | 7.98 |
| CHEMBL47639 | — | — | 1 | 7.40 |
| CHEMBL423844 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45777 | — | Ki | = | 1.81 | nM | 8.74 |
| CHEMBL295827 | — | Ki | = | 4.26 | nM | 8.37 |
| CHEMBL103 | PROGESTERONE | Ki | = | 10.4 | nM | 7.98 |
| CHEMBL47639 | — | Ki | = | 39.8 | nM | 7.40 |
| CHEMBL423844 | — | Ki | = | 80.1 | nM | 7.10 |