Progesterone receptor · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-13Protein identity stays anchored to UniProt P06186. Use UniProt P06186 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06186 as the stable identity anchor, then attach disease evidence before program review.
Progesterone receptor
Review this target as Progesterone receptor, mapped to UniProt P06186. Sequence length is 930 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Progesterone receptor as ChEMBL target CHEMBL3456, mapped to UniProt P06186. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Progesterone receptor is the right protein anchor across sources, using UniProt P06186 as the stable mapping.
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| Preferred Name | Progesterone receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P06186 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Progesterone receptor |
| UniProt Accession | P06186 |
| Component Type | Protein |
| Sequence Length | 930 aa |
Progesterone receptor
Review this target as Progesterone receptor, mapped to UniProt P06186. Sequence length is 930 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL45777 | 8.74 | Ki | 1.81 | Preclinical |
| CHEMBL313220 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL422241 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL315989 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL86310 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL295827 | 8.37 | Ki | 4.26 | Preclinical |
| CHEMBL315991 | 8.28 | IC50 | 5.3 | Preclinical |
| CHEMBL103 | 8.22 | IC50 | 6.0 | Approved |
| CHEMBL86141 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL85157 | 8.19 | IC50 | 6.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 28 | 49 | 7.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 10 | 0 | — |
| assay format | 7 | 0 | — |