Compound Detail
CHEMBL315989
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Basic Information
| ChEMBL ID | CHEMBL315989 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HNPUHUYRWKEFCY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
334.4
MW (Da)
4.49
ALogP
3
HBA
0
HBD
34.9
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL3456 | IC50 | 8.52 | 8.52 | 3.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | IC50 | = | 3.0 | nM | 8.52 | Binding affinity determined by ability to displace [3H]R5020 radioligand using u... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)10016-6 | Progesterone receptor | 1 |
| - | 10.1016/S0960-894X(97)10016-6 | T47D | 1 |
Data from ChEMBL 36 via Core Engine