Assay Detail
Binding
CHEMBL764196
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Dissociation constant for progesterone receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.75 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1161 | MOMETASONE FUROATE | 4.0 | 1 | 10.10 |
| CHEMBL1162 | NORETHINDRONE | 4.0 | 1 | 9.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1161 | MOMETASONE FUROATE | Kd | = | 0.08 | nM | 10.10 |
| CHEMBL1162 | NORETHINDRONE | Kd | = | 0.4 | nM | 9.40 |