Assay Detail
Binding
CHEMBL764419
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Inhibitory activity against HCMV protease by HPLC assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human betaherpesvirus 5 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.59 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL318067 | — | — | 1 | 6.16 |
| CHEMBL317215 | — | — | 1 | 6.14 |
| CHEMBL321046 | — | — | 1 | 5.32 |
| CHEMBL318782 | Dichlon | — | 1 | 5.28 |
| CHEMBL95798 | — | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL318067 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL317215 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL321046 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL318782 | Dichlon | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL95798 | — | IC50 | = | 9100.0 | nM | 5.04 |