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Assay Detail

CHEMBL764437

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Functional
In vitro inhibitory activity against hepatic stages of Plasmodium yoelii yoelii 265 BY
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium yoelii yoelii
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium yoelii yoelii (CHEMBL612328)
Type ORGANISM
Organism Plasmodium yoelii yoelii

Publication

Synthesis of new fluoroquinolones and evaluation of their in vitro activity on Toxoplasma gondii and Plasmodium spp.
Anquetin G, Rouquayrol M, Mahmoudi N, Santillana-Hayat M, Gozalbes R, Greiner J, Farhati K, Derouin F, Guedj R, Vierling P.
Bioorg Med Chem Lett (2004) 14 : 2773 -2776
PubMed 15125930 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.14 4.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL93307 1 4.14
CHEMBL428 TROVAFLOXACIN 4.0 1 4.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL93307 IC50 = 73100.0 nM 4.14
CHEMBL428 TROVAFLOXACIN IC50 = 74000.0 nM 4.13