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Assay Detail

CHEMBL765068

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro inhibition of platelet activating factor (PAF) production in human PMN
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Analogs of the marine natural product scalaradial lacking the ,-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator production
Glaser KB, Sung M, Lock Y, Bauer J, Kubrak D, Kreft A
Bioorg Med Chem Lett (1994) 4 : 1873 -1878
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL487005 SCALARADIAL 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL487005 SCALARADIAL IC50 = 1000.0 nM 6.00