Assay Detail
Binding
CHEMBL765102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di-t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.57 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL16659 | — | — | 1 | 6.10 |
| CHEMBL94361 | — | — | 1 | 5.82 |
| CHEMBL329781 | — | — | 1 | 5.44 |
| CHEMBL94851 | — | — | 1 | 5.28 |
| CHEMBL93712 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL16659 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL94361 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL329781 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL94851 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL93712 | — | IC50 | = | 6000.0 | nM | 5.22 |