Assay Detail
Binding
CHEMBL765136
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In vitro inhibitory activity in the fMLP-stimulated phospholipase (PLD) assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Sch 53823 and Sch 53825, novel fungal metabolites with phospholipase D inhibitory activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.70 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL156779 | — | — | 1 | 4.77 |
| CHEMBL422511 | — | — | 1 | 4.72 |
| CHEMBL153990 | — | — | 1 | 4.62 |
| CHEMBL154853 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL156779 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL422511 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL153990 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL154853 | — | IC50 | > | 50000.0 | nM | - |