Assay Detail
Functional
CHEMBL765198
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Antiviral activity against subtype isolate F strain in PBLs (peripheral blood lymphocytes)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The biological effects of structural variation at the meta position of the aromatic rings and at the end of the alkenyl chain in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.06 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129835 | — | — | 1 | 6.52 |
| CHEMBL340869 | — | — | 1 | 6.12 |
| CHEMBL294840 | — | — | 1 | 5.89 |
| CHEMBL107200 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129835 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL340869 | — | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL294840 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL107200 | — | IC50 | = | 1900.0 | nM | 5.72 |