Assay Detail
Functional
CHEMBL765294
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Antiviral activity against human peripheral blood mononuclear cells, infected with HIV-1(strain LAV).
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity of acyclic 6-(phenylselenenyl)pyrimidine nucleosides against human immunodeficiency viruses in primary lymphocytes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.28 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31871 | HEPT | — | 1 | 5.28 |
| CHEMBL320766 | — | — | 1 | - |
| CHEMBL273401 | — | — | 1 | - |
| CHEMBL278418 | — | — | 1 | - |
| CHEMBL109792 | — | — | 1 | - |
| CHEMBL11762 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31871 | HEPT | EC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL320766 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL273401 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL278418 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL109792 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL11762 | — | EC50 | > | 100000.0 | nM | - |